SUNDAY, JUNE 26
15.00 – 18.30
Registration
19.00 – 22.00
Poster Exhibition and Buffet Dinner
MONDAY, JUNE 27
09.00 – 09.20
Opening of ESMEC 2016
- Gabriele Costantino – President of the Medicinal Chemistry Division of the Italian Chemical Society
- Jordi Gracia– Member of the EFMC Executive Committee
- Carlo De Micheli – Director of the European School of Medicinal Chemistry
Drug discovery: perspectives in the war on cancer
- Marco Mor – University of Parma – Parma (I)
- Antonio Macchiarulo – University of Perugia – Perugia (I)
09.20 – 09.30
Introduction to the session
09.30 – 10.15
Giulio Draetta – University of Texas- Houston (USA)
Changing paradigms in cancer treatment – drug discovery challenges
10.15 – 11.00
Paul W. Manley – Novartis Pharma – Basel (CH)
Discovery of Imatinib and Nilotinib: Targeted ABL kinase inhibitors for the treatment of leukemia
11.00 – 11.30
Coffee Break
11.30 – 12.15
Gianluca Papeo – Nerviano Medical Sciences – Milan (I)
Leveraging DNA Repair defects of Cancer Cells: the Case of PARP Inhibitors
12.15 – 13.00
Manlio Palumbo – University of Padova – Padova (I)
Innovative drugs based on nucleic acids
13.00 – 14.30
Lunch
14.30 – 16.00
Gilberto Spadoni – University of Urbino – Urbino (I)
Poster Session I
16.00 – 18.30
Case Study – Session I
20.30
Dinner
TUESDAY, JUNE 28
09.00 – 09.15
Introduction to the Session
Protein-protein interactions: structures and druggability
- Maria Laura Bolognesi – University of Bologna – Bologna (I)
- Stefania Butini – University of Siena – Siena (I)
09.15 – 10.00
Thomas L. Blundell– University of Cambridge – Cambridge (UK)
Protein-Protein Interactions: Structures and Druggability
10.00 – 10.45
Maurizio Pellecchia – UCR School of Medicine – Riverside (USA)
Protein-protein interactions: challenges and opportunities for the development of novel therapeutics
10.45 – 11.15
Coffee Break
11.15 – 12.00
Maurizio Pellecchia – UCR School of Medicine – Riverside (USA)
Modern drug discovery technologies to tackle protein-protein interactions
12.00 – 12.45
Francesca Bernardini – Polyphor Ltd – Allschwil (CH)
A Novel Class of Antibiotics against MDR Gram-negative ESKAPE Pathogens
12.45 – 14.00
Lunch
14.00 – 15.30
Poster Session II
Gilberto Spadoni – University of Urbino – Urbino (I
15.30 -18.30
Case Study – Session II
20.30
Dinner
WEDNESDAY, JUNE 29
09.00 – 09.15
Introduction to the Session
New avenues in Carbohydrate Chemistry
- Fabrizio Micheli – Aptuit S.r.l. – Verona (I)
- Giampiero Spalluto – University of Trieste – Trieste (I)
09.15 – 10.00
Sabine Flitsch – University of Manchester- Manchester (UK)
Enzymatic Synthesis of Glycoconjugates
10.00 – 10.45
Hermen Overkleeft – University of Leiden- Leiden (NL)
Chemical biology and medicinal chemistry of glycosphingolipid metabolism
10.45 – 11.15
Coffee Break
11.15 – 12.00
Carlo Unverzagt – University of Bayreuth – Bayreth (D)
Convergent synthesis of glycoproteins – biologics from scratch
12.00 – 12.45
Laura Cipolla – University of Milan Bicocca – Milan (I)
Glycochemistry and tissue regeneration: challenges and opportunities
12.45 – 14.00
Lunch
14.00 – 15.00
Mario Varasi – Fondazione-Istituto FIRC di Oncologia Molecolare, Milan (I)
2015 approved drugs: To market! To market!
15.00 – 18.00
Workshop
20.30
Dinner
THURSDAY, JUNE 30
09.00 – 09.15
Introduction to the Session
Hot Topics
- Jordi Gracia – Almirall, S.A. – Sant Feliu de Llobregat (E)
- Gilberto Spadoni – University of Urbino – Urbino (I)
09.15 – 10.00
Marie-Priscille Brun – Sanofi – Vitry-sur Seine (F)
Antibody Drug Conjugates: a new wave of anti-cancer drugs
10.00 – 10.45
Stefano Salmaso – University of Padova – Padova (I)
Supramolecular responsive architectures for smart tumor targeting
10.45 – 11.15
Coffee Break
11.15 – 12.00
Yves P. Auberson – Novartis – Basel (CH)
Medicinal chemists don’t just make drugs – the art of developing medical imaging agents.
12.00 – 12.45
Alleyn Plowright – AstraZeneca – Mölndal (S)
Discovery of Novel Molecules for Therapeutic Heart Regeneration
12.45 – 14.00
Lunch
14.00 – 18.00
Mario Varasi – Fondazione-Istituto FIRC di Oncologia Molecolare, Milan (I)
Presentation and Discussion of Selected Posters
18.00
Carlo De Micheli – University of Milan – Milan (I) – ESMEC Director –
Concluding Remarks
20.30
Gala Dinner
FRIDAY, JULY 1
Leaving of participants