This Year the Scientific Programme Includes the Following Topics:

PROTEOLYSIS TARGETING CHIMERA (PROTAC): FROM MEDICINAL CHEMISTRY TO CLINICAL TRIALS

Alessio CIULLI – University of Dundee (UK)
Targeted protein degradation with small molecules: How PROTACs work
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Peter ETTMAYER – Boehringer Ingelheim, Wien (A)
Lessons learned with co-operativity driven and structure guided PROTAC design
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Michael GÜTSCHOW – University of Bonn (D)
Novel CDK6 PROTACs Recruiting Different Ligases
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Danilo MIRIZZI – Nerviano Medical Sciences (I)
The PROTAC challenge
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Nello MAINOLFI – Kymera Therapeutics, Cambridge (USA)
Targeted Protein Degradation Beyond Oncology

SUSTAINABLE CHEMISTRY APPROACHES TO LEAD DISCOVERY AND CHEMICAL PROCESSES

– Maurizio TADDEI – University of Siena (I)
Streamlined synthetic design for a sustainable access to active pharmaceutical Ingredients
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Irini ABDIAJ – Janssen Pharmaceutical, Toledo (ES)
Continuous Flow in Medicinal Chemistry: opening new chemical space for Drug Discovery
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Fabrizio MICHELI – Aptuit, Evotec, Verona (I)
Dopamine D3 antagonists with modified “amino” region: developability aspects
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Luca DELL’AMICO – University of Padua (I)
Disclosing the Synthetic Potential of Light-Excited Ketones – from the Concepts towards Sustainable Applications

MEDICINAL CHEMISTRY’S RESPONSE TO THE BURDEN OF ANTIBIOTIC RESISTANCE

– Marialuisa MANGONI – Sapienza University of Rome (I)
A lesson from amphibian skin antimicrobial peptides and derivatives for new therapeutic application
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Marc DEVOCELLE – Royal College of Surgeons in Ireland, Dublin (IE)
T.b.d.
– Marco DE VIVO – Istituto Italiano di Tecnologia – Genoa (I)
Mechanistic insights into bacterial group II intron RNA catalysis
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Syma KHALID – University of Southampton (UK)
Molecular Dynamics simulations reveal unexpected details of antibiotic interactions within bacterial cell envelopes

MARKET WATCH: NEW DRUG APPROVAL IN 2020 AND SYNTHETIC STRATEGIES

– Tiziano BANDIERA – Istituto Italiano di Tecnologia – Genoa (I)

As Special Event will be held and Open Webinar titled “Covid and Science”