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MONDAY, JUNE 28<\/strong><\/p>\n 09.00 \u2013 09.20 Opening of ESMEC 2021 PROTEOLYSIS TARGETING CHIMERA (PROTAC): FROM MEDICINAL CHEMISTRY TO CLINICAL TRIALS<\/strong><\/p>\n Morning Session<\/em><\/p>\n Co-chair: Gianluca PAPEO \u2013 Nerviano Medical Sciences (IT) 09.20 \u2013 09.30 Introduction to the Session<\/p>\n 09.30 \u2013 10.15 Alessio CIULLI \u2013 University of Dundee (UK) 10.15 \u2013 11.00 Peter ETTMAYER \u2013 Boehringer Ingelheim, Wien (AT) 11.00 \u2013 11.15 Break<\/p>\n 11.15 \u2013 12.00 Michael G\u00dcTSCHOW \u2013 University of Bonn (DE) 12.00-12.45 Danilo MIRIZZI \u2013 Nerviano Medical Sciences (IT) Afternoon Session<\/em><\/p>\n 15.00 \u2013 17.30 Open Webinar<\/p>\n Round Table: Covid and Science<\/em><\/p>\n Chairman: Gianluca SBARDELLA \u2013 President of the Medicinal Chemistry Division of the Italian Chemical Society (IT)<\/p>\n Participants: Rui MOREIRA – President of the European Federation for Medicinal Chemistry and Chemical Biology (PT) 18.00 \u2013 18.45 Nello MAINOLFI \u2013 Kymera Therapeutics, Cambridge (USA) TUESDAY, JUNE 29<\/strong><\/p>\n Morning Session<\/em><\/p>\n SUSTAINABLE CHEMISTRY APPROACHES TO LEAD DISCOVERY AND CHEMICAL PROCESSES<\/strong><\/p>\n Co-chair: Stefania BUTINI \u2013 University of Siena (IT) 09.00 \u2013 09.15 Introduction to the Session<\/p>\n 09.15 \u2013 10.00 Maurizio TADDEI \u2013 University of Siena (IT) 10.00 \u2013 10.45 Irini ABDIAJ \u2013 Janssen Cilag S.A., Toledo (ES) 10.45 \u2013 11.00 Break<\/p>\n 11.00 \u2013 11.45 Fabrizio MICHELI \u2013 Aptuit S.r.l. \u2013 An Evotec Company, Verona (IT) 11.45 \u2013 12.30 Luca DELL\u2019AMICO \u2013 University of Padua (IT) Afternoon Session<\/em><\/p>\n 15.00 \u2013 17.00 Chairperson: Gilberto SPADONI \u2013 University of Urbino Carlo Bo (IT) 17.00 \u2013 18.00 Assemblea della sezione Giovani della Divisione di Chimica Farmaceutica della SCI<\/p>\n 18.00 Social Event<\/p>\n WEDNESDAY, JUNE 30<\/strong><\/p>\n MEDICINAL CHEMISTRY\u2019S RESPONSE TO THE BURDEN OF ANTIBIOTIC RESISTANCE<\/strong><\/p>\n Morning Session<\/em><\/p>\n Co-chair: Andrea CAVALLI \u2013 University of Bologna (IT) 09.00 \u2013 09.15 Introduction to the Session<\/p>\n 09.15 \u2013 10.00 Marialuisa MANGONI \u2013 Sapienza University of Rome (IT) 10.00 \u2013 10.45 Marc DEVOCELLE \u2013 Royal College of Surgeons in Ireland, Dublin (IE) 10.45 \u2013 11.00 Break<\/p>\n 11.00 \u2013 11.45 Marco DE VIVO \u2013 Istituto Italiano di Tecnologia \u2013 Genoa (IT) 11.45 \u2013 12.30 Syma KHALID \u2013 University of Southampton (UK) Afternoon Session<\/em><\/p>\n 15.00 \u2013 17.00 Open Webinar \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 First edition of the ESMEC Alumni Award<\/em> THURSDAY, JULY 1<\/strong><\/p>\n Chairperson: Antoni TORRENS, Welab, Barcelona (ES)<\/p>\n 09.00 \u2013 10.00 Tiziano BANDIERA \u2013 Istituto Italiano di Tecnologia \u2013 Genoa (IT) 10.00 \u2013 10.15 Break<\/p>\n 10.15 \u2013 12.15 Chairperson: Gilberto SPADONI \u2013 University of Urbino Carlo Bo (IT) 12.15 \u2013 13.00 Marco MACCHIA \u2013 Director of the European School of Medicinal Chemistry [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" MONDAY, JUNE 28 09.00 \u2013 09.20 Opening of ESMEC 2021Giorgio CALCAGNINI \u2013 Rector of the University of Urbino Carlo BoRui MOREIRA \u2013 President of the European Federation for Medicinal ChemistryGianluca SBARDELLA \u2013 President of the Medicinal Chemistry Division of the Italian\u00a0Chemical SocietyMarco MACCHIA \u2013 Director of the European School of Medicinal Chemistry PROTEOLYSIS TARGETING CHIMERA 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Giorgio CALCAGNINI \u2013 Rector of the University of Urbino Carlo Bo
Rui MOREIRA \u2013 President of the European Federation for Medicinal Chemistry
Gianluca SBARDELLA \u2013 President of the Medicinal Chemistry Division of the Italian\u00a0Chemical Society
Marco MACCHIA \u2013 Director of the European School of Medicinal Chemistry<\/p>\n
Tracey PIRALI \u2013 University of Piemonte Orientale (IT)<\/p>\n
Targeted protein degradation with small molecules: How PROTACs work<\/em><\/p>\n
Lessons learned with co-operativity driven and structure guided PROTAC design<\/em><\/p>\n
Towards the Development of PROTACs for the Degradation of CDK6 and Beyond<\/em><\/p>\n
The PROTAC challenge<\/em><\/p>\n
Gabriele COSTANTINO – Director of the Department of Food and Drugs, University of Parma; Vice-President of the Italian Chemical Society (IT)
Emanuele ANDREANO – Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena (IT)
Nir LONDON – Weizmann Institute of Science, Rehovot (IL), COVID Moonshot initiative
Armando GENAZZANI – University of Piemonte Orientale, (IT); Technical and Scientific Committee of the Italian Medicines Agency (AIFA); Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA)
Giovanni MAGA – Director of Institute of Molecular Genetics IGM-CNR, Head of the DNA Enzymology&Molecular Virology Section, National Research Council, Pavia (IT)<\/p>\n
Targeted Protein Degradation Beyond Oncology<\/em><\/p>\n
Antonio MACCHIARULO \u2013 University of Perugia (IT)<\/p>\n
Streamlined synthetic design for a sustainable access to active pharmaceutical<\/em>
ingredients<\/em><\/p>\n
Continuous Flow in Medicinal Chemistry: opening new chemical space for Drug<\/em>
Discovery<\/em><\/p>\n
Dopamine D3 antagonists with modified “amino” region: developability aspects<\/em><\/p>\n
Disclosing the Synthetic Potential of Light-Excited Ketones – from the Concepts towards Sustainable Applications<\/em><\/p>\n
Poster Session<\/p>\n
Paolo GRIECO \u2013 University of Naples (IT)<\/p>\n
A lesson from amphibian skin antimicrobial peptides and derivatives for new therapeutic application<\/em><\/p>\n
Covalent modification of Antimicrobial Peptides<\/em><\/p>\n
Mechanistic insights into bacterial group II intron RNA catalysis<\/em><\/p>\n
Molecular Dynamics simulations reveal unexpected details of antibiotic interactions<\/em>
within bacterial cell envelopes<\/em><\/p>\n
\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Celebration of the 40th Anniversary of the School<\/em>
Chairman: \u00a0 \u00a0 \u00a0 Marco MACCHIA \u2013 Director of the European School of Medicinal Chemistry<\/p>\n
Chairman: \u00a0 \u00a0 \u00a0 Gianluca SBARDELLA\u2013 President of the Medicinal Chemistry Division – SCI<\/p>\n
Market Watch: New Drug Approval in 2020 and Synthetic Strategies<\/em><\/p>\n
Selected oral lectures by participants
Bonnet Maurinne – ICN, Nizza
Cecchini Carlotta – University of Geneva
Introvigne Maria Luisa – University of Modena e Reggio Emilia
Mart\u00ed Mar\u00ed Olaia – Medicinal Chemistry Institute – CSIC
Palomba Tommaso – University of Perugia
Vrettos Erinaios – University of Ioannina<\/p>\n
Awards of selected posters
Concluding remarks<\/p>\n