{"id":309,"date":"2017-10-19T13:25:51","date_gmt":"2017-10-19T13:25:51","guid":{"rendered":"http:\/\/eventi.uniurb.it\/esmec\/?page_id=309"},"modified":"2018-06-25T13:58:18","modified_gmt":"2018-06-25T13:58:18","slug":"programme","status":"publish","type":"page","link":"https:\/\/eventi.uniurb.it\/esmec\/?page_id=309","title":{"rendered":"Programme"},"content":{"rendered":"

[et_pb_section transparent_background=”off” allow_player_pause=”off” inner_shadow=”off” parallax=”off” parallax_method=”on” custom_padding=”54px|0px|54px|0px” padding_mobile=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”off” custom_width_px=”1080px” custom_width_percent=”80%” make_equal=”off” use_custom_gutter=”off” fullwidth=”off” specialty=”off” admin_label=”section” disabled=”off”][et_pb_row make_fullwidth=”off” use_custom_width=”off” width_unit=”off” custom_width_px=”1080px” custom_width_percent=”80%” use_custom_gutter=”off” gutter_width=”3″ padding_mobile=”off” allow_player_pause=”off” parallax=”off” parallax_method=”on” make_equal=”off” column_padding_mobile=”on” parallax_1=”off” parallax_method_1=”on” parallax_2=”off” parallax_method_2=”on” parallax_3=”off” parallax_method_3=”on” parallax_4=”off” parallax_method_4=”on” disabled=”off”][et_pb_column type=”4_4″ disabled=”off” parallax=”off” parallax_method=”on” column_padding_mobile=”on”][et_pb_text background_layout=”light” text_orientation=”left” use_border_color=”off” border_style=”solid” disabled=”off”]<\/p>\n

<\/h3>\n

SUNDAY, JULY 1<\/o:p><\/span><\/p>\n

 <\/o:p><\/span><\/p>\n\n\n\n\n
\n

15.00 – 18.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Registration<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

19.00 – 22.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Putting up of Posters and Dinner<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/o:p><\/span><\/p>\n

MONDAY, JULY 2<\/o:p><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

09.00 – 09.20<\/span><\/o:p><\/span><\/b><\/p>\n<\/td>\n

\n

Opening of ESMEC 2018
<\/span>Gabriele COSTANTINO – President of the Medicinal Chemistry Division of the Italian Chemical Society
Rui MOREIRA – Member of the Executive Committee of the European Federation for Medicinal Chemistry<\/span>
<\/span><\/span>Marco MACCHIA– Director of the European School of Medicinal Chemistry<\/span>
<\/o:p><\/font><\/span><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n\n

“Medicinal chemistry approaches in personalized medicines”<\/span><\/b><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n\n

Co-chair:
Andrea CAVALLI – University of Bologna (I)
Stefania BUTINI – University of Siena (I)<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.20 – 09.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Introduction to the Session<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.30 – 10.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Pier Giuseppe PELICCI – Istituto Europeo di Oncologia – Milan (I)
<\/span>Introductory overview on precision medicine<\/span><\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

10.15 – 11.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Marinella ROBERTI – University of Bologna (I)
Synthetic lethality as a new paradigm for the development of anticancer agents<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

11.00 – 11.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Coffee Break<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

11.30 – 12.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Emanuele GABELLIERI – AC Immune SA, Lausanne (CH)
Discovery of novel PET tracer for the detection of pathological tau aggregated: Towards precision medicine in neurodegenerative diseases<\/span><\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

12.15 – 13.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Alan P. KOZIKOWSKI – StarWise Therapeutics LLC, Madison, WI (USA)
<\/span>Urea-based prostate specific membrane antigen (PSMA) ligands for the diagnosis and therapy (theranostic) of prostate cancer<\/span><\/i><\/p>\n<\/td>\n<\/tr>\n

\n

13.00 – 15.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Lunch<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

15.00 – 17.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Case Studies
Marinella ROBERTI – University of Bologna (I)
<\/span>Development of synthetic lethal candidate leads<\/em> <\/span><\/p>\n

Emanuele GABELLIERI – AC Immune SA (Lausanne, CH)
Design of a suitable PET ligand(s) and the respective precursor(s) starting from the proposed structures<\/em><\/o:p><\/i><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

20.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Dinner<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/o:p><\/span><\/p>\n

<\/h3>\n

TUESDAY, JULY 3<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n\n

“Continuous flow chemistry in drug discovery and development”<\/span><\/b><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n\n

Co-chair:
Paolo GRIECO – University of Naples Federico II (I)
Tracey PIRALI – University of Piemonte Orientale (I)<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.00 – 09.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Introduction to the Session<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.15 – 10.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Andreas KIRSCHNING – Leibniz University of Hannover (D)
Enabling Technologies in Organic Synthesis of Drugs – On Minireactors and Inductive Heating<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

10.00 – 10.45<\/o:p><\/span><\/p>\n<\/td>\n

\n

Antimo GIOIELLO – University of Perugia (I)
<\/span>Medicinal chemistry powered by continuous flow technology – a multifaceted toolbox for compound library building and scale-up processes<\/span><\/i><\/p>\n<\/td>\n<\/tr>\n

\n

10.45 –11.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Coffee Break<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

11.15 – 12.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Marcus BAUMANN – University College Dublin (IRL)
Continuous flow chemistry for readily scaled routes into drug-like entities<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

12.00 – 12.45<\/o:p><\/span><\/p>\n<\/td>\n

\n

Giorgio MARINI – CEM s.r.l., Cologno al Serio, BG (I)
<\/span>Use of microwave technology in different synthetic applications<\/span><\/i><\/p>\n<\/td>\n<\/tr>\n

\n

12.45 – 14.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Lunch<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

14.30 – 18.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Workshop
Bruno CERRA – University of Perugia (I)
Andrew MANSFIELD and Marco GRASSO – SYRRIS<\/span> <\/p>\n

Workshop: Giorgio MARINI – CEM<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

20.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Dinner<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/o:p><\/p>\n

<\/a>WEDNESDAY, JULY 4<\/o:p><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n\n

“Reducing drug attrition rate: predictive PK and ligand residence time”<\/span><\/b><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n\n

Co-chair:
Fabrizio MICHELI – Aptuit S.r.l. – Verona (I)
Antonio MACCHIARULO – University of Perugia (I)<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.00 – 09.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Introduction to the Session<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

09.15 – 10.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Gerard ECKER – University of Vienna (A)
Predicting Ligand Residence Time – it’s all about how long you stay<\/span><\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

10.00 – 10.45<\/o:p><\/span><\/p>\n<\/td>\n

\n

Valerio MAMMOLI – Aptuit S.r.l. – Verona (I)
Optimizing DMPK Properties: The role of pharmacokinetics in drug discovery<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

10.45 – 11.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Coffee Break<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

11.15 – 12.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Gabriele CRUCIANI – University of Perugia (I)
Personalized approaches to clinical trials<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

12.00 – 12.45<\/o:p><\/span><\/p>\n<\/td>\n

\n

Ismael ZAMORA – Lead Molecular Design S.L. (ES)
How structure elucidation of reactive metabolites can help in the toxicity prediction<\/i><\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

12.45 – 14.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Lunch<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

14.30 – 16.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Workshop
Molecular Discovery Ltd, London (UK)<\/font><\/p>\n<\/td>\n<\/tr>\n

16.30 – 18.00<\/span><\/td>\nChairperson: Gilberto SPADONI – University of Urbino (I)<\/span>
Poster Session<\/span><\/td>\n<\/tr>\n
\n

20.30<\/o:p><\/span><\/p>\n<\/td>\n

\n

Gala Party<\/font><\/p>\n<\/td>\n<\/tr>\n

\n

\n<\/td>\n

<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/o:p><\/span><\/p>\n

THURSDAY, JULY 5<\/o:p><\/span><\/p>\n\n\n\n\n\n\n\n\n
<\/td>\nChairperson:<\/span>
Rui MOREIRA – University of Lisbon (P)<\/span><\/td>\n<\/tr>\n
\n

09.00 <\/o:p><\/span>– <\/span>10.00<\/span><\/p>\n<\/td>\n

\n

Tiziano BANDIERA – Istituto Italiano di Tecnologia – Genova (I)
<\/span>Market Watch: New Drug Approvals in 2017 and Synthetic Strategies<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

10.00 <\/o:p><\/span>– <\/span>10.30<\/span><\/td>\nCoffee Break<\/span>
<\/span><\/td>\n<\/tr>\n
10.30 <\/o:p><\/span>– <\/span>12.30<\/span><\/td>\n\n

Chairperson:<\/span> <\/span>Gilberto SPADONI – University of Urbino (I)
<\/span>Selected oral lectures<\/span><\/span><\/p>\n

Federica DALL’OGLIO – University of Milan (I)
Biocatalyzed continuous-flow processes and their application in the synthesis of active pharmaceutical ingredients<\/em><\/span><\/span><\/p>\n

Serena DELLA VOLPE – University of Pavia (I)
Towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modeling approach for the exploration of ligand binding modes<\/em><\/span><\/span><\/p>\n

Anna Corbera DURAN – Institute for Advanced Chemistry of Catalonia, Barcelona (E)
Photo-cardiac modulation without requirement for genetic manipulation using synthetic light-regulated drugs<\/em><\/span><\/span><\/p>\n

Nicolò FANTONI – Dublin City University (IRL)
Artificial metallo-nucleases for gene editing<\/em><\/span><\/span><\/p>\n

Mihaela JURKOVI<\/span><\/span>\u0106 – Fidelta Ltd, Zagreb (HR)
A new Class of the hedgehog signalling pathway modulators<\/em><\/span><\/font><\/p>\n

Nicola LUISE – University of Dundee (UK)
To design and develop semi-saturated bicyclic heterocycles for fragment-based drug discovery (FBDD) campaigns<\/em><\/span><\/font><\/p>\n<\/td>\n<\/tr>\n

12.30 <\/o:p><\/span>– <\/span>13.15<\/span><\/td>\n\n

Marco MACCHIA – University of Pisa (I) – ESMEC Director
Awards of Selected Posters
Concluding Remarks<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

13.15<\/o:p><\/span><\/p>\n<\/td>\n

\n

Lunch and leaving<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n

 <\/o:p><\/span><\/p>\n

PARALLEL EVENTS<\/o:p><\/span><\/p>\n

TUESDAY, JULY 3<\/o:p><\/span><\/p>\n

 <\/o:p><\/span><\/p>\n\n\n\n\n
\n

15.00 – <\/span>17.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Tavola rotonda: <\/o:p><\/span><\/p>\n

Aspetti e opportunità dei progetti Europei <\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

18.00<\/o:p><\/span><\/p>\n<\/td>\n

\n

Assemblea della sezione Giovani della Divisione di Chimica Farmaceutica della SCI<\/o:p><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/o:p><\/p>\n

 <\/o:p><\/p>\n

 <\/o:p><\/p>\n

 <\/o:p><\/p>\n

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SUNDAY, JULY 1   15.00 – 18.30 Registration 19.00 – 22.00 Putting up of Posters and Dinner   MONDAY, JULY 2 09.00 – 09.20 Opening of ESMEC 2018Gabriele COSTANTINO – President of the Medicinal Chemistry Division of the Italian Chemical SocietyRui MOREIRA – Member of the Executive Committee of the European Federation for Medicinal ChemistryMarco MACCHIA– […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":306,"menu_order":20,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-309","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/pages\/309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=309"}],"version-history":[{"count":31,"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/pages\/309\/revisions"}],"predecessor-version":[{"id":487,"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/pages\/309\/revisions\/487"}],"up":[{"embeddable":true,"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=\/wp\/v2\/pages\/306"}],"wp:attachment":[{"href":"https:\/\/eventi.uniurb.it\/esmec\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}