SUNDAY, JULY 2

15.00 – 18.30

Registration

19.00 – 22.00

Putting up of posters and Buffet dinner at the restaurant “Il Castello”, Via del Poggio, Urbino

MONDAY, JULY 3

09.00 – 09.20

Opening of ESMEC 2017
Gabriele COSTANTINO – President of the Medicinal Chemistry Division of the Italian Chemical Society
Rui MOREIRA – Member of the EFMC Executive Committee

 

Polypharmacology and Multi-targeting paradigms in drug discovery: complexity against complexity

 

Co-chair:
Maria Laura BOLOGNESI – University of Bologna (I)
Stefania BUTINI – University of Siena (I)

09.20 – 09.30

Introduction to the session

09.30 – 10.15

Rona R. RAMSAY – University of St Andrews – St Andrews (UK)
Designing monoamine oxidase inhibitors in multi-target drugs to address neuropathology

10.15 – 11.00

Christophe ROCHAIS – Université de Caen Normandie – Caen (F)
Modulating 5-HTS receptors in alzheimer’s disease treatment: a polypharmacology approach

11.00 – 11.30

Coffee Break

11.30 – 12.15

Maria Fernanda BORGES – University of Porto (P)
Neurodegenerative diseases and therapy: challenges and opportunities

12.15 – 13.00

Holger Stark – Heinrich-Heine-University, Duesseldorf (D)
Multiple Targeting with Histamine H3 Receptor Ligands

13.00 – 15.00

Lunch

15.00 – 16.00

Case Study, Serena Tongiani – Angelini SpA – Pomezia, I
Novel Approaches to Drug Design and Development: Case Studies in Molecular Structure, Computation, Ligand-Receptor Interaction and Modelling

16.00 – 17.30

Case Study,  Christophe Rochais , Université de Caen Normandie – Caen (F)
Polypharmacology in Drug Discovery

20.30

Dinner

TUESDAY, JULY 4

 

Structures and models in drug design

 

Co-chair:
Antonio MACCHIARULO – University of Perugia (I)
Marco MOR – University of Parma (I)

09.00 – 09.15

Introduction to the Session

09.15 – 10.00

Gerhard HESSLER – Sanofi-Aventis Deutschland GmbH – Frankfurt (D)
Successful structure-based drug design – A case study

10.00 – 10.45

Giulio VISTOLI – University of Milan (I)
From molecular docking to virtual screening approaches: an in silico travel poking around the recognition event

10.45 – 11.15

Coffee Break

11.15 – 12.00

Pierre Ducrot – Institut de Recherches Servier – Suresnes (F)
Predicting ligand-target residence time using Smoothed-Molecular Dynamics

12.00 – 12.45

Giovanni BOTTEGONI – Heptares Therapeutics, Welwyn Garden City (UK)
Computer-assisted design of multi-target compounds

12.45 – 14.30

Lunch

14.30 – 16.00

Case study, Sergio Decherchi, Biki Technologies – Genoa, I

16.00 – 18.00

Mini-workshop, Andrea Ciacci, S-IN – Vicenza, I

20.30

Dinner

WEDNESDAY, JULY 5

 

Peptides: from synthesis to applications

 

Co-chair:
Fabrizio MICHELI – Aptuit S.r.l. – Verona (I)
Giampiero SPALLUTO – University of Trieste (I)

09.00 – 09.15

Introduction to the Session

09.15 – 10.00

Paolo ROVERO – University of Florence (I)
From the discovery of solid-phase synthesis to the development of new drugs: half a century of peptide chemistry from the viewpoint of a medicinal chemist

10.00 – 10.45

Paolo GRIECO – Federico II University– Neaples (I)
From Peptides to Peptidomimetics: Design and Synthesis of Potential Drug

10.45 – 11.15

Coffee Break

11.15 – 12.00

Jeffrey W. BODE – ETH – Zurich (CH)
Chemical Protein Synthesis, the KAHA Ligation

12.00 – 12.45

Fernando FORMAGGIO – University of Padua (I)
Synthesis, conformation and bioactivity of selected peptaibiotics

12.45 – 14.30

Lunch

14.30 – 16.30

Case Study, Francesca Benevelli, Bruker Italia – Milan, I

16.30 – 18.00

Chairperson: – Gilberto SPADONI – University of Urbino (I)
Poster Session

20.30

Gala Party

THURSDAY, JULY 6

 

Beyond PhD: building up an appealing scientific and professional profile

 

Co-chair:
Rui MOREIRA – University of Lisbon (P)
Gilberto SPADONI – University of Urbino (I)

09.00 – 10.30

Donna HURYN – University of Pittsburgh (USA)
The publishing Process

10.30 – 10.50

Coffee Break

10.50 – 12.50

Oral lectures by participants.

    12.50 – 13.10

    Chairperson: Maria Laura BOLOGNESI – University of Bologna (I)
    CMC award of Selected Posters

    13.10

    Concluding Remarks

    13.30

    Lunch and Leaving

    PARALLEL EVENTS
    TUESDAY, JULY 4

    15.00 – 17.00

    Tavola rotonda
    La chimica farmaceutica ed i corsi di dottorato: prospettive ed opportunità

    18.30 Assemblea della sezione Giovani della Divisione di Chimica Farmaceutica della SCI